LIFE

LIFE - Longitudinal Indian Family hEalth

LIFE questionnaires
LIFE fortnight reports

INVESTIGATORS:

SHARE INDIA , MediCiti Institute of Medical Sciences.
Kalpana Betha, MD, Professor and Head of Department, OBY, MIMS
K. Govind Narsingrao MD, Professor and Head of Department, Community Health, MIMS
PS Reddy, MD, Chairman of SHARE INDIA


University of Pittsburgh Consultant:
Catherine L. Haggerty, PhD, MPH, Associate Professor and Director of the Reproductive, Perinatal and Pediatric Epidemiology Area of Emphasis
University of Pittsburgh Graduate School of Public Health, Department of Epidemiology, Pittsburgh, PA, USA http://www.publichealth.pitt.edu/home/directory/catherine-l-haggerty

DESIGN PAPER:
Kusneniwar GN, Whelan RM, Betha K, Robertson JM, Ramidi PR, Balasubramanian K, Kamasamudram V, Haggerty CL, Bunker CH, Reddy PS. Cohort Profile: The Longitudinal Indian Family hEalth (LIFE) Pilot Study, Telangana State, India. International Journal of Epidemiology. 2017 Jun 1; 46(3):788-789j. PMID: 27649805. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837391/

OBJECTIVES

  1. The LIFE (Longitudinal Indian Family hEalth) study is being conducted in villages of Medchal Mandal, R.R.District, Telangana, India.This is a long-term research study that will examine socio-economic and environmental influences on children’s health and development in India.

  2. The main aim of the study is to understand the link between the environmental conditions in which Indian women conceive, go through their pregnancy and give birth, and their physical and mental health during this period.

  3. The LIFE Pilot is a prospective cohort study of Indian women followed through conception, pregnancy, and delivery, and the physical and mental health and development of their children.

  4. The LIFE Pilot study is designed to identify the root causes of conditions excessively prevalent in India, including adverse pregnancy outcomes and childhood diseases and developmental disorders.

  5. Since 2009, 1227 women aged between 15 and 35 years were recruited before conception or within 14 weeks of gestation. Women were followed through pregnancy, delivery, and postpartum. Follow-up of children is ongoing. Baseline data were collected from husbands of 642 women.

  6. Anthropometric measurements, biological samples and detailed questionnaire data were collected during registration, the first and third trimesters, delivery and at 1 month postpartum. Anthropometric measurements and health questionnaire data are obtained for each child, and a developmental assessment is done at 1, 6, 12, 18, 24, 36, 48 and 60 months. At 36 months, each child is screened for development and mental health problems. Questionnaires are completed for pregnancy loss and death of children under 5 years old. The LIFE Biobank preserves over 6000 samples
EXPECTED OUTCOME

By linking multiple maternal and environmental factors to multiple health outcome measures, the LIFE study has the potential to pinpoint the root causes of many conditions that are excessively prevalent in India, including low birth weight, pre-term birth, other adverse pregnancy outcomes and diseases or development disorders of early childhood.

TO DISCUSS POTENTIAL COLLABORATION PLEASE CONTACT:

Dr. PS Reddy, psreddypittsburgh@gmail.com
Dr. K. Govind Narsingrao MD, drkgn2012@gmail.com
Kalpana Betha, MD, kalpanabasany@gmail.com
Catherine L. Haggerty, PhD, MPH, haggerty@pitt.edu