Indo-American artificial heart program
Maternal Nutritional Status and Pancreatic Beta Cell Function in Asian Indian Infants
Center for Chronic Disease Control ( CCDC), New Delhi.
Moon-shot: Develop total artificial heart.
Immediate: Promote bioengineering research in Engineering Institutes of India in collaboration with Medical Institutions, Engineering Industries and Medical device developers.
- Dr. P. S. Reddy, Chairman, SHARE INDIA.
- Dr. A. G. K. Gokhale, Cardiothoracic Surgeon, Apollo Hospitals, Hyderabad.
- Dr. B. M. Gandhi, Chief Executive Officer, Neo Biomed Services, New Delhi
- Dr. A. Subhanada Rao, Director, Advancement and Research, Sree Nidhi Institute of Science and Technology.
Jump start facilitated by
United States of America
University of Pittsburgh, Pittsburgh, PA, USA:
- Dr. Robert L. Kormos, Prof, of Cardiac Surgery
- Dr. Harvey Borovetz, Prof, of Bioengineering
- Mr. Salim Olia, Artificial Heart Engineer
- Dr. Kalpana Betha, SHARE INDIA, MIMS
Cornell University, New York, USA
- Dr. James Antaki, Professor of Bioengineering
INTEGRIS Nazih Zuhdi Transplant Institute, INTEGRIS Baptist Medical Center Oklahoma City, OK, USA.
- Dr. James Long, Director.
Birla Institute of Technology - BITS PILANI, Hyderabad
- Dr. Suman Kapur, Senior Professor, Department of Biological Sciences;
- Dr. Srinivas Prakash Regalia, Professor and Head, Department of Mechanical Engineering;
- Dr. Sanket Goel, Associate Professor, Department of Electronics and Electrical Engineering.
Chaitanya Bharathi Institute of Technology (CBIT)
- Dr. P. Ravinder Reddy, Principal
- Mr. Rugveda, Research Associate.
Sree Nidhi Institute of Science and Technology(SNIST)
- Dr. A. Subhanada Rao, Director, Advancement and Research.
- Dr. K.S.R. Siva Sai, Professor and Head, Department of Biotechnology.
- Dr. A. Purushotham, Professor, Department of Mechanical Engineering.
Kakatiya Institute of Technology and Science, Warangal
- Dr. Venu Madhav Kotturu, Prof, and Head, Dept. of Electronics & Instrumentation Engineering
- Dr. Ganesh Kumar Gampa, Associate Professor, Department of Mechanical Engineering
- Dr. A. Madhuker Reddy, Asst. Professor, Department of Electrical and Electronics Engineering
- Dr. K. Eswaraiah, Professor, Department of Mechanical Engineering
- Dr. Vijay V. Yeldandi, Clinical Professor of Medicine and Surgery, University of Illinois and member, SHARE INDIA.
Laxven Systems, Hyderabad:
Mr. Ramesh Reddy, Chairman and Managing Director.
Shree Pacetronix Ltd., Indore:
- Mr. Atul Sethi, Chairman and Managing Director
- Mr. Vikas Gokhale, Technical Director.
Shrishti Resins, Hyderabad
- Mr. K.P. Reddy, Chairman and Managing Director.
Sri Koteswara Cam Systems Pvt Ltd., Hyderabad:
- Mr. Koteshwara Rao, Managing Director.
Path Care Lab. Pvt Ltd., Hyderabad:
- Dr. G. V. Prasad, Chairman and Managing Director
- Ms. Nandini Prasad, Director.
Kaarthik Moulds & Dies, Hyderabad:
- Mr. Nagendra Chowdary G.
- Mr. K. Vijay Saradhi
Funding source: Self funding by Indian Institutions aided by SHARE INDIA and SHARE USA
Development Approach of the Project
M/s. Laxven Systems is developing Centrifugal Levitation Pump for extracorporeal LVAD and CBIT is developing Centrifugal Pump with magnetically coupled impellor and Pivot bearing. KITS also entered into the scene recently and is working on Centrifugal Pump. SNIST is working on fabrication of Centrifugal Pump impellor and housing by Injection molding. SNIST is also working on Axial Levitation Pump for implant.
Status of the Project
1. HEMOLYSIS TESTING OF PUMP WITH HUMAN BLOOD
- Test protocol for testing of Centrifugal pump was finalized with the help of Dr.Salim Olia. Test was conducted as per the protocol at BITS, Hyderabad campus initially with original CENTRIMAG pump and later with centrifugal pump developed by Mr. Rugveda. The test was conducted for three hours. Prof. Harvey and Dr. Salim Olia witnessed the testing. Blood samples were taken every hour and tested for free Hemoglobin using SPECTROMETER. It was concluded that blood tested with Mr. Rugveda's pump was hemolysed where as blood tested with CENTRIMAG was not hemolysed. It is evident from the color of the blood also.
- Test method was established at MediCiti Hospital also. All chemicals and equipment is available now. Spectrometer is calibrated. Next series of tests can be done at MediCiti.
2. PLAN OF ACTION FOR SOLVING THE PROBLEM OF HEMOLYSIS
- Improving the surface finish of pump.
SLR 3D printer will give good finish. Some spares are awaited for this machine. As soon as it is ready, printing will be done.
- Redesign of pivot bearing
Redesign of pivot bearing is to be done. ROTAFLOW extra corporal centrifugal pump has the similar pivot bearing. This pump was sent by Prof. Antaki. It was cut open. Bearing has a ball which moves on spherical surface. This design will be adapted and realized soon
- CFD studies have to be done for this pump considering HEMOLYSIS and THROMBOSIS. Mr. Rugveda may do these studies at CORNELL when he goes there in June for Internship
A heavy duty 3D printing machine is received by CBIT. Pump can be printed with Polycarbonate material on this machine. This is the ultimate material to be used which is bio compatible. After the machine is installed this will be done.
3. CFD STUDIES AT KITS
HP-28 workstation and ANSYS 19 software was purchased by KITS, Warangal at a cost of Rsl 9 Lakhs. CFD studies were conducted and H-Q curves generated for Rugveda's pump.
4. LEVITATION PUMP AT LAXVEN SYSTEMS
Fine tuning of Levitation motor was done by improving the processing speed . Final PCB's were ordered and received. It is under integration and testing. It will be ready by 15* April, 2019.
5. MACHINNING OF TITANIUM IMPELLER AT KAARTHIK MOULDS AND DIES
Titanium material, which is bio compatible is received from DRDO on special request. Impeller was machined by precision machining on 4 axis machining centre. Mr. Nagendra Chowdary is working on this. Drawings are generated for CENTRIMAG pump with the help of DRDO. The pump housing and impeller
will be 3D printed with poly carbonate in CBIT with newly installed 3D printer
WINTER INSTITUTE IN GLOBAL HEALTH WORKSHOP AT BITS
Artificial heart team participated in this International workshop at BITS and gave 5 talks on 16th Jan., 2019.